Information for
Medical Professionals

View General Monkeypox Information


Guide for Medical Providers in Delaware

The Delaware Division of Public Health has outlined helpful information and resources for medical professionals in Delaware. Review the materials below, if you have questions please contact us.

Contact Delaware’s Office of Infectious Disease Epidemiology (OIDE)


Normal Business Hours Contact Number: 302-744-4990

Monday through Friday from 8 a.m. to 4:30 p.m.


24/7 Emergency Contact Number: 1-888-295-5156



If a provider is unable to collect specimen or if a person is under/uninsured or does not have access to a health care provider, DPH/OIDE will coordinate specimen collection with one of the Delaware Public Health Clinics, Delaware Public Health Laboratory (DPHL), and the CDC, if a patient meets the criteria for a suspected case.



Antivirals should be considered for patients who may be at high risk of severe disease, refer to Interim Clinical Guidance for the Treatment of Monkeypox.



Currently, the Centers for Disease Control and Prevention is not encouraging vaccination against monkeypox for the broader public or for everyone who is sexually active.  Delaware is currently offering vaccination to people at higher risk of exposure, including:

  • Persons known or presumed to be exposed to someone with MPX in the last 14 days
  • Certain individuals who have sex with men and who have had multiple sex partners within the past 14 days
  • Those living with HIV or who are receiving HIV PrEP
  • Immunocompromised persons (including those with cancer, solid organ or stem cell transplants, those taking immunosuppressive therapy, and individuals with autoimmune disease)
  • Those treated for a sexually transmitted infection (STI) in the last six months
  • Individuals traveling to an area with community spread of MPX cases
  • Those engaging in high-risk activities, including sexual practices, that increase exposure to MPX, such as:
    • Gay, bisexual, and other men who have sex with men and have had multiple, or any, anonymous sexual partners in a social network experiencing monkeypox activity, this includes meeting partners through an online website, digital application (“app”), or social event (e.g., a bar or party)
    • Transgender women or nonbinary persons assigned male at birth who have sex with men
    • Sex workers (of any sexual orientation/gender)
    • Staff (of any sexual orientation/gender) at establishments where sexual activity occurs (e.g., bathhouses, saunas, sex clubs)
  • People who fall into any of the identified high-risk categories who are also experiencing homelessness or incarceration
  • People, particularly adolescent or young adult males, might consider waiting 4 weeks after MPX vaccination before receiving a COVID-19 vaccine, because of the unknown risk for myocarditis and/or pericarditis after JYNNEOS. The CDC is not recommending vaccination for the general public or for all sexually active persons. To reduce their risk of contracting or spreading MPX, individuals should limit direct contact with anyone with a concerning rash, limiting the number of intimate partners, talking openly with intimate contacts about recent behaviors, and not sharing bedding, towels and eating or drinking utensils with anyone who does.

The JYNNEOS EUA allows use of the vaccine in individuals less than 18 years old without providing a minimum age. There is limited data for those 5 months and younger. When considering post-exposure prophylaxis (PEP) for a child or adolescent, clinicians should first consult their jurisdictional health department (Jurisdictional Contacts). Jurisdictional health departments can facilitate consultation with CDC for guidance regarding pediatric use of JYNNEOS vaccine or other PEP modalities, when needed.

FDA Fact Sheet for Health Care Providers: Emergency Use Authorization of Jynneos for Prevention of Monkeypox

All requests for vaccines should be sent to DPH Office of Infectious Disease Epidemiology (OIDE) at 302-744-4990 (business hours) or 1-888-295-5156 (24/7). OIDE business hours are Monday through Friday from 8 a.m. to 4:30 p.m.

All wasted vials must be reported using the vaccine return form to the Immunizations Program. Only vials are reported as waste and not doses, for example if a vial has been broken it would be reported as waste. If a vial only contained three doses instead of five, then the provider does NOT need to report the two doses that were not able to be pulled as waste. 

All provider requests to administer MPX vaccine should be the same as the request for test kits and be sent to OEMS using the SHOC form.


Reporting of Cases

All suspected cases should be reported to OIDE

Once OIDE is notified of a suspected/confirmed monkeypox case, they will help to facilitate obtaining vaccine and antiviral supply through the CDC and the Investigational New Drug (IND) application process. A SHOC Resource Request form must be completed by facility requesting vaccine/antivirals.

All suspected cases should be reported to OIDE at 302-744-4990

OIDE Business hours (Monday-Friday from 8:00am to 4:30pm)

After hours/Weekends/holidays

To report after hours or on weekends or holidays, fill out Morbidity Card and send to

Please include details on where the specimen is located (i.e. specify hospital campus, building) and the estimated time when it will be ready for pickup by courier services.


CDC Announcements

Update for Clinicians on Testing and Treatment for Monkeypox 7.28.2022




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